Adderall -  Amphetamine/Dextroamphetamine

What Is Adderall XR?

Adderall is a central nervous system stimulant (amphetamine).  Adderall is used to treat attention deficit hyperactivity disorder (ADHD) in children 6 years of age and older and in adults. 

Who Should Not Take Adderall ?

You should not take Adderall if you have:

• A heart defect

• Other heart problems, including high blood pressure, and heart or blood vessel disease

• Overactive thyroid

• Glaucoma

• A history of drug abuse

Never take Adderall  if you are taking a drug used to treat depression, called a Monoamine Oxidase Inhibitor (MAOI), or if you have stopped taking an MAOI in the last 14 days. Taking Adderall  close in time to an MAOI can result in serious, sometimes fatal, reactions, including:

• High body temperature
• Coma
• Seizures (convulsions)

MAOI drugs include Nardil (phenelzine sulfate), Parnate (tranylcypromine sulfate), Marplan (isocarboxid), and other brands.

What Are The Risks?

• Sudden deaths: See FDA Alert. 

• Abuse potential:  See Warning.

• Worsening mental illness (psychosis):  Adderall  may make symptoms of existing mental illness worse.
• Possible decreased growth and weight loss: Adderall  may decrease growth and cause weight loss.  Children who take it for a long time should have their growth and body weight measured regularly.

• Increased tics: Adderall  may worsen tics and Tourette’s disorder. 

• Pregnancy: Tell your healthcare professional if you are or may be pregnant because your baby may be premature or have a low birth weight.  Also, your baby may show withdrawal symptoms, such as agitation and drowsiness. 
• Breast feeding: Do not breast feed while taking Adderall  because it can pass into your breast milk. 
• Other side effects include loss of appetite, difficulty sleeping, dry mouth, headaches, and mood changes.
• Tell your healthcare professional about any medical conditions you have in addition to those already mentioned in this information sheet.

Are There Any Interactions With Drugs or Foods?

• Adderall may interact with other medicines.  These interactions can cause serious side effects. Tell your healthcare professional about all medicines, vitamins, and herbal supplements you take, especially:
  • Those used to treat depression, known as tricyclic antidepressants and monoamine oxidase inhibitors (MAOI)
  • Antacids
  • Those used to treat urinary problems
  • Diuretics
  • Propoxyphene (Darvon, Darvocet), a pain medicine

 How Do I Take Adderall ?

• Adderall is taken by mouth, in the morning, with or without food, exactly as prescribed by your healthcare professional.
• Swallow Adderall  capsules whole or open the capsule and sprinkle the contents on a spoonful of applesauce.  Take right away without chewing.

This information is provided by the U.S. Food & Drug Administration.  

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Last updated on: May 06, 2008